电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CD55 抗体 (PE)

CD55 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal NaM16-4D3 PE
产品编号 ABIN1106466
发货至: 中国
  • 抗原 See all CD55 抗体
    CD55 (Complement Decay-Accelerating Factor (CD55))
    适用
    • 109
    • 35
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    宿主
    • 69
    • 66
    • 6
    • 6
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 81
    • 69
    • 2
    单克隆
    标记
    • 73
    • 17
    • 16
    • 10
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD55 antibody is conjugated to PE
    应用范围
    • 98
    • 76
    • 47
    • 38
    • 33
    • 25
    • 16
    • 15
    • 14
    • 13
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    The antibody detects human CD55. Other species not tested. Cellular expression: platelets, monocytes, lymphocytes and erythrocytes.
    纯化方法
    Affinity chromatography
    克隆位点
    NaM16-4D3
    亚型
    IgG1
    Top Product
    Discover our top product CD55 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
  • 抗原
    CD55 (Complement Decay-Accelerating Factor (CD55))
    别名
    CD55 / DAF (CD55 产品)
    别名
    CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
    背景
    CD55 is expressed as a 60-70 kD single chain Glycosylphosphatidylinositol (GPI) anchored glycoprotein (in erythrocytes). In other cells the molecular weight is somewhat larger. It is comprised of four N-terminal short consensus repeats (SCR) modules (4 Cys in 1-3,2-4 linkage) with C3b/C4b binding and regulator activity in SCR 2,3,4. CD55 is often involved in the protection of cells from autologous compliment-mediated injury and are partially or completely lacking in peripheral blood cells. CD55 inhibits the formation and accelerates the decay of C3/C5 convertase complexes both of classical and alternative pathway [1]. CD55 sets a protective barrier threshold against inappropriate complement activation and deposition on plasma membranes, especially by the classical pathway of complement activation, by limiting formation and half-life of the C3 convertases. Since CD55 is well known membrane-associated complement regulator protein, like CD59, and present on all blood cells, anti-CD55 and anti-CD59 appear to be the most effective Mabs to detect very minor negative cell subsets (less than 1 % on erythrocytes or less than 5 % on PMN leukocytes.Synonyms: Complement decay-accelerating factor
    基因ID
    1604
    NCBI登录号
    NP_000565
    UniProt
    P08174
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity
You are here:
客服