CD55 抗体 (PE)
Quick Overview for CD55 抗体 (PE) (ABIN1106466)
抗原
See all CD55 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody detects human CD55. Other species not tested. Cellular expression: platelets, monocytes, lymphocytes and erythrocytes.
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纯化方法
- Affinity chromatography
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亚型
- IgG1
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anti-Complement Decay-Accelerating Factor (CD55) (AA 35-134) antibody
CD55 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-285) antibodyCD55 适用: 人 WB, ELISA, IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 40-300) antibodyCD55 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 51-79) antibodyCD55 适用: 人 WB, FACS, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-134) antibodyCD55 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (Center) antibodyCD55 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 254-372) antibodyCD55 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-126) antibodyCD55 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) antibodyCD55 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 1A5 unconjugated Recombinant Antibody
anti-Complement Decay-Accelerating Factor (CD55) antibodyCD55 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal F4-29D9 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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别名
- CD55 / DAF
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背景
- CD55 is expressed as a 60-70 kD single chain Glycosylphosphatidylinositol (GPI) anchored glycoprotein (in erythrocytes). In other cells the molecular weight is somewhat larger. It is comprised of four N-terminal short consensus repeats (SCR) modules (4 Cys in 1-3,2-4 linkage) with C3b/C4b binding and regulator activity in SCR 2,3,4. CD55 is often involved in the protection of cells from autologous compliment-mediated injury and are partially or completely lacking in peripheral blood cells. CD55 inhibits the formation and accelerates the decay of C3/C5 convertase complexes both of classical and alternative pathway [1]. CD55 sets a protective barrier threshold against inappropriate complement activation and deposition on plasma membranes, especially by the classical pathway of complement activation, by limiting formation and half-life of the C3 convertases. Since CD55 is well known membrane-associated complement regulator protein, like CD59, and present on all blood cells, anti-CD55 and anti-CD59 appear to be the most effective Mabs to detect very minor negative cell subsets (less than 1 % on erythrocytes or less than 5 % on PMN leukocytes.Synonyms: Complement decay-accelerating factor
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基因ID
- 1604
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NCBI登录号
- NP_000565
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UniProt
- P08174
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity
抗原
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