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CD55 抗体

CD55 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal 2C6 unconjugated
产品编号 ABIN1106464
发货至: 中国
  • 抗原 See all CD55 抗体
    CD55 (Complement Decay-Accelerating Factor (CD55))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD55 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein A agarose
    免疫原
    Human adenocarcinoma cell line (PC3)
    克隆位点
    2C6
    亚型
    IgG1
    Top Product
    Discover our top product CD55 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD55 (Complement Decay-Accelerating Factor (CD55))
    别名
    CD55 / DAF (CD55 产品)
    别名
    CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
    背景
    CD55, also known as decay-accelerating factor (DAF), is a GPI-anchored membrane inhibitor of complement. It inhibits complement activation by interfering with the function of C3 and C5 convertases in both the classical and alternative pathways. CD55 is expressed on most cells to protect them from complement-mediated attack. CD55 and other membrane complement regulatory proteins (CD46 and CD59) are frequently overexpressed on cancer cells, possibly as a mechanism for cancer cells to overcome lysis by complement. Virus-receptor interactions have been elucidated for several viruses that use CD55 as an adhesion or invasion receptor, including enterovirus, echovirus, and coxsackie B virus. Moreover, CD55 also interacts with an epidermal growth factor-seven-span transmembrane (EGF-TM7) receptor, CD97. CD97 antigen becomes immediately up-regulated on most leukocytes during activation and is constitutively expressed by macrophages, dendritic cells, and some epithelial tumors.Synonyms: Complement decay-accelerating factor
    基因ID
    9606
    UniProt
    P08174
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity
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