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CD55 抗体

This anti-CD55 antibody is a 小鼠 单克隆 antibody detecting CD55 in FACS 和 IP. Suitable for 人.
产品编号 ABIN1106464
发货至: 中国

Quick Overview for CD55 抗体 (ABIN1106464)

抗原

See all CD55 抗体
CD55 (Complement Decay-Accelerating Factor (CD55))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD55 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

2C6
  • 交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A agarose

    免疫原

    Human adenocarcinoma cell line (PC3)

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD55 (Complement Decay-Accelerating Factor (CD55))

    别名

    CD55 / DAF

    背景

    CD55, also known as decay-accelerating factor (DAF), is a GPI-anchored membrane inhibitor of complement. It inhibits complement activation by interfering with the function of C3 and C5 convertases in both the classical and alternative pathways. CD55 is expressed on most cells to protect them from complement-mediated attack. CD55 and other membrane complement regulatory proteins (CD46 and CD59) are frequently overexpressed on cancer cells, possibly as a mechanism for cancer cells to overcome lysis by complement. Virus-receptor interactions have been elucidated for several viruses that use CD55 as an adhesion or invasion receptor, including enterovirus, echovirus, and coxsackie B virus. Moreover, CD55 also interacts with an epidermal growth factor-seven-span transmembrane (EGF-TM7) receptor, CD97. CD97 antigen becomes immediately up-regulated on most leukocytes during activation and is constitutively expressed by macrophages, dendritic cells, and some epithelial tumors.Synonyms: Complement decay-accelerating factor

    基因ID

    9606

    UniProt

    P08174

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity
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