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CD46 抗体

CD46 适用: 人 WB, IP, Func, EIA 宿主: 小鼠 Monoclonal M177 unconjugated
产品编号 ABIN1106417
发货至: 中国
  • 抗原 See all CD46 抗体
    CD46
    适用
    • 111
    • 39
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    • 10
    • 1
    宿主
    • 84
    • 47
    • 2
    小鼠
    克隆类型
    • 73
    • 60
    单克隆
    标记
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    • 1
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    This CD46 antibody is un-conjugated
    应用范围
    • 86
    • 76
    • 42
    • 40
    • 33
    • 14
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    • 9
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    Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)
    特异性
    The monoclonal antibody M177 recognizes CD46, also designated membrane cofactor protein (MCP).
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    免疫原
    Purified MCP
    克隆位点
    M177
    亚型
    IgG1
    Top Product
    Discover our top product CD46 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.1 % bovine serum albumin
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    CD46
    别名
    CD46 / MCP (CD46 产品)
    别名
    AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
    背景
    CD46 is a 45-70 kDa protein with genetic and tissue-specific heterogeneity. It is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to inhibit complement activation on host tissue. It performs this function by serving as a cofactor which binds to C3b and C4b. This binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. It also serves as a receptor for measles virus. Four isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. CD46 cDNA encodes a signal sequence followed by four complement control protein domains (also called short consensus repeats (SCR).Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
    基因ID
    4179
    NCBI登录号
    NP_002380
    UniProt
    P15529
    途径
    Regulation of Actin Filament Polymerization
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