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CD4 抗体

CD4 适用: 人 FACS 宿主: 小鼠 Monoclonal 4H5 unconjugated
产品编号 ABIN1106337
发货至: 中国
  • 抗原 See all CD4 抗体
    CD4
    适用
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    宿主
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    小鼠
    克隆类型
    • 474
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    单克隆
    标记
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    This CD4 antibody is un-conjugated
    应用范围
    • 498
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with CD4 antigen.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein A agarose
    免疫原
    PHA-activated human CD4+ T-cells
    克隆位点
    4H5
    亚型
    IgG1
    Top Product
    Discover our top product CD4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    CD4
    别名
    CD4 (CD4 产品)
    背景
    The T cell receptor for antigen (TCR) is a membrane-bound member of the immunoglobulin superfamily (IgSF) that recognizes a complex of antigen bound to self major histocompatibility complex (MHC) molecules expressed on the cell-surface of antigen-presenting cells (APC). Both cytotoxic and helper T cells typically respond to antigen which is associated with different types of MHC molecules, class I and II, respectively. CD4 is a 55-60 kDa cell-surface glycoprotein, which participates in the molecular complexes involved both in T cell development and its antigen recognizing activity, by binding to the nonpolymorphic region of class II MHC. This interaction results in increased intercellular adhesion and enhanced stimulation of T cells by signal transduction which is mediated by intracellular molecules. CD4 is also considered as a stage marker of T cell development in thymus, for it is expressed on the cell surface in a stage specific manner, during T cell development.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
    基因ID
    920
    NCBI登录号
    NP_000607
    UniProt
    P01730
    途径
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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