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CD4 抗体

This anti-CD4 antibody is a 小鼠 单克隆 antibody detecting CD4 in FACS. Suitable for 人.
产品编号 ABIN1106337
发货至: 中国

Quick Overview for CD4 抗体 (ABIN1106337)

抗原

See all CD4 抗体
CD4

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

4H5
  • 特异性

    This antibody reacts with CD4 antigen.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A agarose

    免疫原

    PHA-activated human CD4+ T-cells

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store (in aliquots) at -20 °C.
  • 抗原

    CD4

    别名

    CD4

    背景

    The T cell receptor for antigen (TCR) is a membrane-bound member of the immunoglobulin superfamily (IgSF) that recognizes a complex of antigen bound to self major histocompatibility complex (MHC) molecules expressed on the cell-surface of antigen-presenting cells (APC). Both cytotoxic and helper T cells typically respond to antigen which is associated with different types of MHC molecules, class I and II, respectively. CD4 is a 55-60 kDa cell-surface glycoprotein, which participates in the molecular complexes involved both in T cell development and its antigen recognizing activity, by binding to the nonpolymorphic region of class II MHC. This interaction results in increased intercellular adhesion and enhanced stimulation of T cells by signal transduction which is mediated by intracellular molecules. CD4 is also considered as a stage marker of T cell development in thymus, for it is expressed on the cell surface in a stage specific manner, during T cell development.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

    基因ID

    920

    NCBI登录号

    NP_000607

    UniProt

    P01730

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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