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CD37 抗体

The 小鼠 单克隆 anti-CD37 antibody (Clone IPO-24) (ABIN1106328) specifically detects CD37 in IHC (p), IHC (fro) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN1106328
发货至: 中国
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Quick Overview for CD37 抗体 (ABIN1106328)

抗原

See all CD37 (TSPAN26) 抗体
CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD37 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

IPO-24
  • 特异性

    This antibody reacts with CD37 antigen (Human), 40-52 kDa glycoprotein. IPO-24 reacts with Human B cell lines Daudi, Raji, Namalva, Ramos and CABIL, whereas T cell lines CEM, Molt-4, Jurkat, MT-4, H9 and non-lymphoid cell lines MeWo and A-431 are not labelled. IPO-24 stains B cell follicles and the most strongly labelled elements are mantle zone lymphoid cells. Neutrofils, macrophages, thymocytes and dendritic reticulum cells are negative.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Purified

    免疫原

    IPO-24 was generated after immunization of BALB/c mice with spleen cells of a patient with hairy cell leukemia. Mice splenocytes were fused with the P3-X63-Ag8.653 mouse myeloma cell line.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

    别名

    CD37

    背景

    CD37 is a membrane protein of the tetraspanin superfamily, which includes CD9, CD53, CD81, and the R2 antigen among others. Many of these molecules are expressed on leukocytes and have been implicated in signal transduction, cell to cell interactions, and cellular activation and development. The antigen CD37 defined by IPO-24 is B lineage restricted and is strongly expressed throughout B cell ontogeny from pre-B cells untill the plasmoblasts. CD37 is an extensively glycosylated molecule and usually two and sometimes three N-linked carbohydrate chain are attached to the protein. Synonyms: Leukocyte antigen CD37, TSPAN26, Tetraspanin-26

    基因ID

    951

    NCBI登录号

    NP_001765

    UniProt

    P11049

    途径

    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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