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TLR4 抗体 (Biotin)

TLR4 适用: 人 FACS 宿主: 小鼠 Monoclonal 3C3 Biotin
产品编号 ABIN1106217
发货至: 中国
  • 抗原 See all TLR4 抗体
    TLR4 (Toll-Like Receptor 4 (TLR4))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TLR4 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    免疫原
    CHO cells expressing chimeric human TLR4/MD-2 fusion protein
    克隆位点
    3C3
    亚型
    IgG1
    Top Product
    Discover our top product TLR4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    TLR4 (Toll-Like Receptor 4 (TLR4))
    别名
    CD284 / TLR4 (TLR4 产品)
    背景
    TLRs belong to a family of proteins that specifically recognize and sense microbial products. They are highly conserved throughout evolution. In Drosophila, toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. TLRs identified as type I transmembrane signalling receptors act as innate immune recognition receptors against many pathogens.TLR4 is a functional receptor for gram-negative bacterial lipopolysaccharides (LPS). TLR4 associates with MD-2 which is absolutely required for LPS-induced activation of TLR4. TLR4 has been identified next to MD-2 and CD14 as a receptor that is central to the innate immune response to LPS of Gram-negative bacteria.Synonyms: Toll-like receptor 4
    NCBI登录号
    NM_138554
    UniProt
    O00206
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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