TLR1 抗体
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北京 101111
Quick Overview for TLR1 抗体 (ABIN1106186)
抗原
See all TLR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody GD2.F4 reacts with human TLR1. Does not react with TLR2 or TLR4.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein G
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免疫原
- TLR1Fc
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亚型
- IgG1
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anti-Toll-Like Receptor 1 (TLR1) (AA 30-290) antibody
TLR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 101-200) antibodyTLR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 114-339) antibodyTLR1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 8-3# unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 350-404) antibodyTLR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 25-580) antibodyTLR1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 25-134) antibodyTLR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) antibody (PE-Cy7)TLR1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, FACS 宿主: 兔 Polyclonal PE-Cy7
anti-Toll-Like Receptor 1 (TLR1) (AA 321-420) antibodyTLR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 605-785) antibodyTLR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 1 (TLR1) (AA 114-339) antibodyTLR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- TLR1 (Toll-Like Receptor 1 (TLR1))
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别名
- CD281 / TLR1
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背景
- Toll-like receptors (TLR) are highly conserved throughout evolution and play an essential role in recognizing conserved motifs found in various pathogens and initiating an appropriate innate immune response. In human, ten members of the TLR family have been identified as type I transmembrane signaling receptors containing multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Mammalian responsiveness to microbial products may be mediated by combinations of TLRs, for example a co-operative effect is observed between TLR1 and TLR2 in response to bacterial lipoproteins. On the other hand, TLR 1 was shown to have the capacity to abrogate TLR4 signaling. In general, TLR1 is expressed at higher levels as compared to other TLRs. The highest expression of TLR1 is found in monocytes but it can also be expressed by macrophages, dendritic cells, B, T, and NK cells. In recent studies, several human TLR1 polymorphisms have been associated with impaired mycobacterial signaling and susceptibility to tuberculosis.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein
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基因ID
- 9606
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UniProt
- Q15399
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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