CD21 抗体 (PE)
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- 抗原 See all CD21 (CR2) 抗体
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD21 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Clone B-ly4 produces mouse IgG1 immunoglobulins directed against a 145 kDa polypeptide of the C3d receptor. Clone B-ly4 was clustered at the Leucocyte Typing Workshop IV [5].
- 纯化方法
- Affinity chromatography
- 克隆位点
- B-ly4
- 亚型
- IgG1
- Top Product
- Discover our top product CR2 Primary Antibody
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anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 142-240) antibody
CR2 适用: 人 FACS, IHC, WB, ELISA, IF, StM, Coat 宿主: 小鼠 Monoclonal CR2-2754 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人 FACS, IHC, WB, ELISA, IF 宿主: 兔 Monoclonal 16F10 unconjugated Recombinant Antibody
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 300-590) antibodyCR2 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 740-964) antibodyCR2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2D2H6 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 981-1092) antibodyCR2 适用: 人, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 44-196) antibodyCR2 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal CR2-1952 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 142-240) antibodyCR2 适用: 人 FACS, IHC, WB, IF, StM 宿主: 兔 Monoclonal CR2-3124R unconjugated Recombinant Antibody
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, Pig, Cow, 犬 FACS, IHC (fro) 宿主: 小鼠 Monoclonal LT21 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 5F2 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
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- 抗原
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
- 别名
- CD21 (CR2 产品)
- 背景
- The CD21 antigen is expressed on mature B cells, follicular dendritic cells and pharyngeal and cervical epithelial cells [1,2]. CD21, also known as the Complement receptor type 2 (CR2) or Epstein-Barr virus (EBV) receptor, is a receptor for the C3 activation fragments iC3b and C3d. CD21 is part of a multimeric complex on B cells which includes CD19 and CD81 [3]. The ligand for CD21 is generated during activation of complement by the attachment of C3d to potential antigen. This creates fusion proteins that may cross-link the CD19-CD21-CD81 complex to sIg on antigen-specific B cells. The resulting signal transduction lowers the threshold for cellular activation. This enables an antibody reaction to natural protein antigens containing only one or a few epitopes and therefore unable to effectively cross-link Ig molecules on specific B cells. For example, keyhole limpet hemocyanin (KLH) immune complexes can be taken up and processed by all CR2-bearing B cells, regardless of their antigen specificity. KLH immune complexes taken up this way by non-specific B cells were shown to be presented to KLH-specific, MHC class II Th cells. CD23 may also serve as a ligand for CD21 [3].Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor
- 基因ID
- 1380
- NCBI登录号
- NP_001006659
- UniProt
- P20023
- 途径
- Complement System
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