CD21 抗体
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北京 101111
Quick Overview for CD21 抗体 (ABIN1106056)
抗原
See all CD21 (CR2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Clone B-ly4 produces mouse IgG1 immunoglobulins directed against a 145 kDa polypeptide of the C3d receptor. Clone B-ly4 was clustered at the Leucocyte Typing Workshop IV [5].
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纯化方法
- Affinity chromatography
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亚型
- IgG1
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anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 142-240) antibody
CR2 适用: 人 FACS, IHC, WB, IF, ELISA, StM, Coat 宿主: 小鼠 Monoclonal CR2-2754 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 300-590) antibodyCR2 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Monoclonal 16F10 unconjugated Recombinant Antibody
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 740-964) antibodyCR2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2D2H6 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 981-1092) antibodyCR2 适用: 人, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 44-196) antibodyCR2 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal CR2-1952 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 142-240) antibodyCR2 适用: 人 FACS, IHC, WB, IF, StM 宿主: 兔 Monoclonal CR2-3124R unconjugated Recombinant Antibody
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, Pig, Cow, 犬 FACS, IHC (fro) 宿主: 小鼠 Monoclonal LT21 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 5F2 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
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- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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别名
- CD21
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背景
- The CD21 antigen is expressed on mature B cells, follicular dendritic cells and pharyngeal and cervical epithelial cells [1,2]. CD21, also known as the Complement receptor type 2 (CR2) or Epstein-Barr virus (EBV) receptor, is a receptor for the C3 activation fragments iC3b and C3d. CD21 is part of a multimeric complex on B cells which includes CD19 and CD81 [3]. The ligand for CD21 is generated during activation of complement by the attachment of C3d to potential antigen. This creates fusion proteins that may cross-link the CD19-CD21-CD81 complex to sIg on antigen-specific B cells. The resulting signal transduction lowers the threshold for cellular activation. This enables an antibody reaction to natural protein antigens containing only one or a few epitopes and therefore unable to effectively cross-link Ig molecules on specific B cells. For example, keyhole limpet hemocyanin (KLH) immune complexes can be taken up and processed by all CR2-bearing B cells, regardless of their antigen specificity. KLH immune complexes taken up this way by non-specific B cells were shown to be presented to KLH-specific, MHC class II Th cells. CD23 may also serve as a ligand for CD21 [3].Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor
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基因ID
- 1380
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NCBI登录号
- NP_001006659
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UniProt
- P20023
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途径
- Complement System
抗原
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