DC-SIGN/CD209 抗体 (FITC)
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- 抗原 See all DC-SIGN/CD209 (CD209) 抗体
- DC-SIGN/CD209 (CD209) (CD209)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DC-SIGN/CD209 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- This antibody reacts with the C-type lectin, DC-SIGN (CD209), exclusively expressed on human dendritic cells (DC).
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein G
- 克隆位点
- DCN47-5
- 亚型
- IgG1
- Top Product
- Discover our top product CD209 Primary Antibody
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anti-CD209 (CD209) (AA 70-404) antibody
CD209 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, FACS, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal C209-1781 unconjugated
anti-CD209 (CD209) (AA 270-404) antibodyCD209 适用: 人 WB, FACS, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 5C2A6 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 FACS, IHC, IP, IHC (p) 宿主: 大鼠 Monoclonal h209 unconjugated
anti-CD209 (CD209) (AA 1-404) antibodyCD209 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-CD209 (CD209) (AA 115-238) antibodyCD209 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, FACS, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal rC209-1781 unconjugated Recombinant Antibody
anti-CD209 (CD209) (AA 271-380) antibodyCD209 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 FACS, IHC, ICC 宿主: 小鼠 Monoclonal UW60-1 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.02 % sodium azide, 1 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2 - 8 °C.
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- 抗原
- DC-SIGN/CD209 (CD209) (CD209)
- 别名
- CD209 / DC-SIGN (CD209 产品)
- 别名
- CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, cd209 antibody, CLEC4M antibody, si:ch211-224h1.3 antibody, CD209 antibody, CIRE antibody, Dcsign antibody, SIGN-R1 antibody, SIGNR5 antibody, Cd209 antibody, CD209 molecule antibody, CD209a antigen antibody, CD209 antigen-like protein D antibody, CD209c molecule antibody, CD209 antigen antibody, CD209 antibody, cd209 antibody, Cd209a antibody, LOC100529184 antibody, Cd209c antibody, LOC100460708 antibody, LOC105484282 antibody
- 背景
- DC are specialized antigen presenting cells and bridge the innate and the adaptive immune system. They provide high levels of costimulation necessary for activation of both naive and antigen-experienced T-cells. Immature DC are capable to migrate to inflammatory sites, capture antigen and process it internally to form MHC-peptide complexes. Following antigen uptake, DC undergo maturation and migrate to lymphoid organs where they can present MHC-peptide complexes to resting T-cells and drive T-cell proliferation. During differentiation and maturation of DC, several phenotypic surface markers are expressed: CD1a, CD4, CD11, CD40, CD86, and HLA-DR. Immature DC predominantly express CCR5 which enables DC to migrate to inflammatory sites, whereas mature DC express high levels of CXCR4, a receptor that facilitates migration to lymphoid organs.DC also express DC-specific, ICAM-3 grabbing, nonintegrin (DC-SIGN), a 44 kDa C-type lectin that binds to the HIV-1 envelope glycoprotein gp120, ICAM-3 on T-cells and ICAM-2 on endothelial cells. HIV virions are able to infect cells expressing CD4 and the chemokine co-receptors CCR5 or CXCR4 and can attach to DC-SIGN to extend virion lifespan. Therefore, DC are candidates for HIV-1 infection. DC-SIGN-ICAM-3 binding is integrin-independent but calcium-dependent and antibodies reactive against DC-SIGN can be used to study DC-SIGN-ICAM3 binding.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
- UniProt
- Q9NNX6
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