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DC-SIGN/CD209 抗体

CD209 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal UW60-1 unconjugated
产品编号 ABIN1106050
发货至: 中国
  • 抗原 See all DC-SIGN/CD209 (CD209) 抗体
    DC-SIGN/CD209 (CD209) (CD209)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This DC-SIGN/CD209 antibody is un-conjugated
    应用范围
    • 69
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    The mouse monoclonal antibody UW60.1 recognizes CD209 (DC-SIGN), a 44 kDa transmembrane receptor expressed on the surface of dendritic cells and macrophages.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein-A affinity chromatography
    纯度
    > 95 % pure (by SDS-PAGE)
    免疫原
    CD209-His-tagged fusion protein
    克隆位点
    UW60-1
    亚型
    IgG1
    Top Product
    Discover our top product CD209 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, approx. pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DC-SIGN/CD209 (CD209) (CD209)
    别名
    CD209 / DC-SIGN (CD209 产品)
    背景
    CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
    基因ID
    9606
    UniProt
    Q9NNX6
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