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DC-SIGN/CD209 抗体

This 小鼠 单克隆 antibody specifically detects DC-SIGN/CD209 in FACS 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN1106050
发货至: 中国
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Quick Overview for DC-SIGN/CD209 抗体 (ABIN1106050)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DC-SIGN/CD209 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

UW60-1
  • 特异性

    The mouse monoclonal antibody UW60.1 recognizes CD209 (DC-SIGN), a 44 kDa transmembrane receptor expressed on the surface of dendritic cells and macrophages.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein-A affinity chromatography

    纯度

    > 95 % pure (by SDS-PAGE)

    免疫原

    CD209-His-tagged fusion protein

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, approx. pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    CD209 / DC-SIGN

    背景

    CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

    基因ID

    9606

    UniProt

    Q9NNX6
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