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CCR6 抗体 (N-Term)

This anti-CCR6 antibody is a 兔 多克隆 antibody detecting CCR6 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1105993
发货至: 中国

Quick Overview for CCR6 抗体 (N-Term) (ABIN1105993)

抗原

See all CCR6 抗体
CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

适用

  • 63
  • 15
  • 12
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 46
  • 14
  • 3
  • 2
  • 1

克隆类型

  • 45
  • 18
  • 2
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CCR6 antibody is un-conjugated

应用范围

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  • 22
  • 16
  • 15
  • 12
  • 6
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody detects CD196 / CCR6 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Immunogen affinity purified

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminal of human CCR6 .Remarks: Sequence is identical to the related rat and mouse sequence.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

    别名

    CD196 / CCR6

    背景

    CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.Synonyms: C-C CKR-6, C-C chemokine receptor type 6, CC-CKR-6, CCR-6, CKRL3, CMKBR6, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, GPR-CY4, GPR29, LARC receptor, STRL22

    基因ID

    1235

    NCBI登录号

    NP_004358

    UniProt

    P51684

    途径

    cAMP Metabolic Process
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