CCR6 抗体 (N-Term)
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Quick Overview for CCR6 抗体 (N-Term) (ABIN1105993)
抗原
See all CCR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects CD196 / CCR6 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Immunogen affinity purified
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminal of human CCR6 .Remarks: Sequence is identical to the related rat and mouse sequence.
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亚型
- IgG
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anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibody
CCR6 适用: 人 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 7C6D9 unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 201-300) antibodyCCR6 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (C-Term) antibodyCCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 322-374) antibodyCCR6 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (N-Term) antibodyCCR6 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibodyCCR6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibodyCCR6 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
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别名
- CD196 / CCR6
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背景
- CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.Synonyms: C-C CKR-6, C-C chemokine receptor type 6, CC-CKR-6, CCR-6, CKRL3, CMKBR6, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, GPR-CY4, GPR29, LARC receptor, STRL22
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基因ID
- 1235
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NCBI登录号
- NP_004358
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UniProt
- P51684
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途径
- cAMP Metabolic Process
抗原
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