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CCR3 抗体

CCR3 适用: 人 FACS 宿主: 小鼠 Monoclonal 444-11 unconjugated
产品编号 ABIN1105989
发货至: 中国
  • 抗原 See all CCR3 抗体
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    适用
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    宿主
    • 54
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    小鼠
    克隆类型
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    • 1
    单克隆
    标记
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    This CCR3 antibody is un-conjugated
    应用范围
    • 51
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with CD193. The antibody has also been reported to inhibit chemotactic migration of monocyte-derived DCs to RANTES (Ref.4). It suppresses the capacity of monocyte-derived DCs to stimulate allogenetic TCs proliferation and TCs derived IFN-γ secretion (Ref.4).
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein A agarose
    免疫原
    Human CCR3 expressing transfectant (mouse pre-B cell lymphoma B300-19)
    克隆位点
    444-11
    亚型
    IgG1
    Top Product
    Discover our top product CCR3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
    别名
    CD193 / CCR3 (CCR3 产品)
    别名
    CC-CKR-3 antibody, CD193 antibody, CKR3 antibody, CMKBR3 antibody, CC-CKR3 antibody, Cmkbr1l2 antibody, Cmkbr3 antibody, C-C motif chemokine receptor 3 antibody, chemokine (C-C motif) receptor 3 antibody, CCR3 antibody, Ccr3 antibody
    背景
    Dendritic cells (DCs) are major antigen presenting cells (APCs) capable of stimulation resting T cells (TCs) in the primary immune response and are more potent APCs than peripheral blood monocytes or B cells. Several CC and CXC chemokines receptors were found to be expressed on some DCs and these molecules have been implicated to mediate in part the trafficking of DCs from blood to tissues and then to lymph nodes, where they form a close association with TCs in the process of antigen presentation. Recent studies have shown that CD191/CCR1 and CD193/CCR3 are potentially involved in antigen-presenting cell function of human DCs.Synonyms: C-C CKR-3, C-C chemokine receptor type 3, CC-CKR-3, CCR-3, CKR3, CMKBR3, Eosinophil eotaxin receptor
    基因ID
    1232
    NCBI登录号
    NP_001828
    UniProt
    P51677
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