TYROBP 抗体
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北京 101111
Quick Overview for TYROBP 抗体 (ABIN110575)
抗原
See all TYROBP 抗体适用
宿主
克隆类型
标记
应用范围
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- 4 °C
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- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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别名
- DAP12
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背景
- : DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is a disulfide-bonded homodimer. Crosslinking of DAP12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.
抗原
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