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- 抗原 See all Caspase 2 (CASP2) 抗体
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects Caspase-2 (C-term). No cross reactivity with other proteins.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat. - 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- Synthetic peptide mapping at the C-terminal of Human Caspase 2 .Remarks: Sequence is identical to the related Rat and Mouse sequence.
- 亚型
- IgG
- Top Product
- Discover our top product CASP2 Primary Antibody
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anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 334-452) antibody
CASP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) antibodyCASP2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 153-452) antibodyCASP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 198-226) antibodyCASP2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) antibodyCASP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3D4 unconjugated Recombinant Antibody
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (Cleaved-Gly170) antibodyCASP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 2-452) antibodyCASP2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 121-220) antibodyCASP2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (Ser197) antibodyCASP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (N-Term) antibodyCASP2 适用: 人, 小鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- 别名
- Caspase-2 (CASP2 产品)
- 别名
- xCaspase-2 antibody, Caspase-2 antibody, ICH-1 antibody, Nedd2 antibody, CASP-2 antibody, ICH1 antibody, NEDD-2 antibody, NEDD2 antibody, PPP1R57 antibody, ICH-1L/1S antibody, ICH1L1S antibody, caspase 2 antibody, caspase 2 L homeolog antibody, caspase-2 antibody, CASP2 antibody, casp2.L antibody, CpipJ_CPIJ008254 antibody, Casp2 antibody
- 背景
- Caspase-2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. activation of caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli. Caspase-2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2
- 基因ID
- 835
- NCBI登录号
- NP_116764
- UniProt
- P42575
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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