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c-MYC 抗体 (AA 408-439)

Name: c-MYC 抗体 (AA 408-439)
SKU: ABIN1105578
Availability: OutOfStock

MYC 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), IP 宿主: 小鼠 Monoclonal IMD-3 unconjugated

产品编号 ABIN1105578

发货至: 中国

Datasheet as PDF

抗原 See all c-MYC (MYC) 抗体

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
抗原表位
55

44

41

37

24

21

19

16

15

11

10

7

7

6

6

6

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 408-439
适用
352

169

122

15

14

13

13

13

9

9

8

6

6

6

5

4

3

3

2

2

2

1

1

1

1

1
人, 小鼠, 大鼠
宿主
282

89

7

3

2

1
小鼠
Compatible Secondaries
克隆类型
275

108
单克隆
标记
188

31

24

24

9

9

9

9

9

9

8

7

5

5

5

5

5

3

2

2

2

2

2

2

2

1

1

1

1

1

1
This c-MYC antibody is un-conjugated
应用范围
284

140

91

79

76

58

53

28

26

14

14

13

12

11

7

4

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

特异性

This antibody recognizes Human c-Myc.

纯化方法

Affinity Chromatography

免疫原

Synthetic peptide corresponding to residues 408-439 of the Human p62c-Myc protein.

克隆位点

IMD-3

亚型

IgG2a

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MYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibody
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应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
溶解方式

Restore with 1.2 % Sodium Acetate or Neutral PBS

浓度

0.1 mg/mL

缓冲液

1.2 % Sodium Acetate, 0.01 mg Sodium Azide, 2 mg BSA

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

别名

C-Myc (MYC 产品)

别名

MRTL antibody, MYCC antibody, bHLHe39 antibody, c-Myc antibody, CMYC antibody, c-myc antibody, C-MYC antibody, LOC100136746 antibody, ARC antibody, B430311C09Rik antibody, MYC antibody, NOP antibody, Nop30 antibody, RNCMYC antibody, mMyc antibody, AU016757 antibody, Myc2 antibody, Niard antibody, Nird antibody, cmyc antibody, zc-myc antibody, c-myc II antibody, myc-B antibody, myc2 antibody, myc1 antibody, CMyc antibody, zgc:55680 antibody, CG10798 antibody, D-Myc antibody, DM antibody, DMYc antibody, Dm antibody, Dmel\CG10798 antibody, Dmyc antibody, EG:BACN5I9.1 antibody, anon-WO03040301.171 antibody, bHLHe57 antibody, c-MYC antibody, d-myc antibody, dMYC antibody, dMyc antibody, dMyc1 antibody, da antibody, dm antibody, dm/dMyc antibody, dm/myc antibody, dmyc antibody, dmyc1 antibody, l(1)G0139 antibody, l(1)G0354 antibody, l(1)G0359 antibody, myc antibody, MYC proto-oncogene, bHLH transcription factor antibody, v-myc myelocytomatosis viral oncogene homolog antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, myelocytomatosis oncogene antibody, MYC proto-oncogene, bHLH transcription factor a antibody, MYC proto-oncogene, bHLH transcription factor L homeolog antibody, MYC proto-oncogene, bHLH transcription factor S homeolog antibody, v-myc myelocytomatosis viral oncogene homolog (avian) antibody, MYC proto-oncogene, bHLH transcription factor b antibody, CG10798 gene product from transcript CG10798-RB antibody, MYC antibody, LOC100136746 antibody, Nol3 antibody, Myc antibody, myca antibody, myc.L antibody, myc.S antibody, mycb antibody

背景

C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells,in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64

基因ID

4609

NCBI登录号

NP_002458

UniProt

P01106

途径

p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect