MMP2 抗体
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北京 101111
Quick Overview for MMP2 抗体 (ABIN110556)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- 4 °C
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP2 (Mammalian Matrix Metalloproteinase, 72kDa Type IV Collagenase, Gelatinase-A)
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背景
- The mammalian matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes1. After cleavage of a signal peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N- terminal propeptide domain is cleaved to generate the active forms of MMP2 . MMP-2 (72 kDa type IV collagenase, Gelatinase-A) contain the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling.
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途径
- Activation of Innate immune Response
抗原
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