PLAP 抗体
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Quick Overview for PLAP 抗体 (ABIN1105297)
抗原
See all PLAP (ALPP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody clone V17.1 reacts with alkaline phosphatase, an enzym widely used in immunodection tests. Can be used for detection of Alkaline Phophatase and for amplification of Alkaline Phophatase reactions (APAP).
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纯化方法
- Purified
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免疫原
- A BALB/c Mouse was immunized with Alkaline Phophatase.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or -20 °C for longer.
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- PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
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物质类
- Tag
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背景
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.Synonyms: Alkaline phosphatase, Alkaline phosphatase Regan isozyme, PLAP-1, placental type
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基因ID
- 250
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NCBI登录号
- NP_001623
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UniProt
- P05187
抗原
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