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MMP2 抗体 (AA 242-396)

This anti-MMP2 antibody is a 小鼠 单克隆 antibody detecting MMP2 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1098146
发货至: 中国

Quick Overview for MMP2 抗体 (AA 242-396) (ABIN1098146)

抗原

See all MMP2 抗体
MMP2 (Matrix Metalloproteinase 2 (MMP2))

适用

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  • 2
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宿主

  • 149
  • 55
  • 1
小鼠

克隆类型

  • 137
  • 68
单克隆

标记

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  • 3
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  • 1
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  • 1
  • 1
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  • 1
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  • 1
  • 1
  • 1
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This MMP2 antibody is un-conjugated

应用范围

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  • 27
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Western Blotting (WB), ELISA

克隆位点

4D1E2
  • 抗原表位

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    • 2
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    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 242-396

    原理

    MMP2 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human MMP2 (AA: 242-396) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Langers, Verspaget, Hawinkels, Kubben, van Duijn, van der Reijden, Hardwick, Hommes, Sier: "MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients." in: British journal of cancer, Vol. 106, Issue 9, pp. 1495-8, (2012) (PubMed).

    Hajighasemi: "Profiles of MMP-2 expression in Jurkat, Molt-4 and U937 cells." in: Iranian journal of immunology : IJI, Vol. 8, Issue 2, pp. 120-6, (2011) (PubMed).

  • 抗原

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    别名

    MMP2

    背景

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    73.8 kDa

    基因ID

    4313

    UniProt

    P08253

    途径

    Activation of Innate immune Response
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