MEF2C 抗体 (AA 1-125)
Quick Overview for MEF2C 抗体 (AA 1-125) (ABIN1098145)
抗原
See all MEF2C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-125
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原理
- MEF2C Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human MEF2C (AA: 1-125) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C." in: PLoS ONE, Vol. 6, Issue 11, pp. e27165, (2011) (PubMed).
: "Myocyte enhancer factor 2c, an osteoblast transcription factor identified by dimethyl sulfoxide (DMSO)-enhanced mineralization." in: The Journal of biological chemistry, Vol. 286, Issue 34, pp. 30071-86, (2011) (PubMed).
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: "VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C." in: PLoS ONE, Vol. 6, Issue 11, pp. e27165, (2011) (PubMed).
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- MEF2C (Myocyte Enhancer Factor 2C (MEF2C))
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别名
- MEF2C
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背景
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This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
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分子量
- 51.2 kDa
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UniProt
- Q06413
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling
抗原
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