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NEFH 抗体 (AA 968-1020)

This anti-NEFH antibody is a 小鼠 单克隆 antibody detecting NEFH in IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1098127
发货至: 中国

Quick Overview for NEFH 抗体 (AA 968-1020) (ABIN1098127)

抗原

See all NEFH 抗体
NEFH (Neurofilament, Heavy Polypeptide (NEFH))

适用

  • 127
  • 97
  • 76
  • 60
  • 41
  • 33
  • 24
  • 22
  • 13
  • 13
  • 9
  • 9
  • 9
  • 7
  • 7
  • 5
  • 2
  • 2
  • 1
  • 1

宿主

  • 80
  • 63
  • 9
小鼠

克隆类型

  • 98
  • 54
单克隆

标记

  • 95
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NEFH antibody is un-conjugated

应用范围

  • 101
  • 60
  • 48
  • 30
  • 27
  • 24
  • 21
  • 18
  • 16
  • 14
  • 13
  • 13
  • 11
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), ELISA

克隆位点

8H10
  • 抗原表位

    • 16
    • 10
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 968-1020

    原理

    NEFH Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).

    Sellner, Patel, Dassan, Brown, Petzold: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).

  • 抗原

    NEFH (Neurofilament, Heavy Polypeptide (NEFH))

    别名

    NEFH

    背景

    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

    分子量

    112.4 kDa

    基因ID

    4744

    UniProt

    P12036
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