NEFH 抗体 (AA 968-1020)
Quick Overview for NEFH 抗体 (AA 968-1020) (ABIN1098127)
抗原
See all NEFH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 968-1020
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原理
- NEFH Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).
: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).
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: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).
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- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
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别名
- NEFH
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背景
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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
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分子量
- 112.4 kDa
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基因ID
- 4744
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UniProt
- P12036
抗原
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