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NEFH 抗体 (AA 968-1020)

NEFH 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 8H10 unconjugated
产品编号 ABIN1098127
发货至: 中国
  • 抗原 See all NEFH 抗体
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    抗原表位
    • 15
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 968-1020
    适用
    • 107
    • 77
    • 61
    • 47
    • 29
    • 23
    • 14
    • 12
    • 9
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 65
    • 55
    • 7
    小鼠
    克隆类型
    • 82
    • 45
    单克隆
    标记
    • 79
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEFH antibody is un-conjugated
    应用范围
    • 79
    • 41
    • 37
    • 28
    • 22
    • 20
    • 20
    • 13
    • 13
    • 12
    • 11
    • 10
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    原理
    NEFH Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.
    克隆位点
    8H10
    亚型
    IgG1
    Top Product
    Discover our top product NEFH Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).

    Sellner, Patel, Dassan, Brown, Petzold: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).

  • 抗原
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    别名
    NEFH (NEFH 产品)
    背景
    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

    分子量
    112.4 kDa
    基因ID
    4744
    UniProt
    P12036
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