FOXP1 抗体 (AA 481-677)
Quick Overview for FOXP1 抗体 (AA 481-677) (ABIN1098120)
抗原
See all FOXP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 481-677
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原理
- FOXP1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human FOXP1 (AA: 481-677) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).
: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).
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: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).
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- FOXP1 (Forkhead Box P1 (FOXP1))
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别名
- FOXP1
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背景
- This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 75.3 kDa
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UniProt
- Q9H334
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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