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CD6 抗体 (AA 472-668)

This anti-CD6 antibody is a 小鼠 单克隆 antibody detecting CD6 in IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1098118
发货至: 中国

Quick Overview for CD6 抗体 (AA 472-668) (ABIN1098118)

抗原

See all CD6 抗体
CD6

适用

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宿主

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  • 2
小鼠

克隆类型

  • 84
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  • 3
单克隆

标记

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This CD6 antibody is un-conjugated

应用范围

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  • 37
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  • 9
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  • 1
Immunohistochemistry (IHC), ELISA

克隆位点

6B9
  • 抗原表位

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    AA 472-668

    原理

    CD6 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD6 (AA: 472-668) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Alonso, Buors, Le Dantec, Hillion, Pers, Saraux, Montero, Marianowski, Loisel, Devauchelle, Youinou, Renaudineau: "Aberrant expression of CD6 on B-cell subsets from patients with Sjögren's syndrome." in: Journal of autoimmunity, Vol. 35, Issue 4, pp. 336-41, (2010) (PubMed).

    Sarrias, Farnós, Mota, Sánchez-Barbero, Ibáñez, Gimferrer, Vera, Fenutría, Casals, Yélamos, Lozano: "CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 28, pp. 11724-9, (2007) (PubMed).

  • 抗原

    CD6

    别名

    CD6

    背景

    This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    71.8 kDa

    基因ID

    923

    UniProt

    P30203
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