CEACAM1/5 抗体
This anti-CEACAM1/5 antibody is a 小鼠 单克隆 antibody detecting CEACAM1/5 in FACS, WB, ELISA, cELISA 和 IHC (fro). Suitable for 人.
Quick Overview for CEACAM1/5 抗体 (ABIN108735)
抗原
CEACAM1/5
(Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This CEACAM1/5 antibody is un-conjugated
应用范围
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Cell-ELISA (cELISA), Immunohistochemistry (Frozen Sections) (IHC (fro))
克隆位点
4-3-17
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特异性
- Anti-human CEACAM1, 5 (BGP, CEA, CD66a,e)
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纯化方法
- Protein G
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免疫原
- immunisation with extracted protein of CEACAM5
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亚型
- IgG1
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5) (N-Term) antibody
CEACAM1/5 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 Western blot: 4 µg/mL
Immunohistology: 1-2 µg/10^6 cells (on cryosections)
For each application a titration should be performed to determine the optimal concentration. -
说明
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Synonyms: CD66ae, BGP, CEA
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C
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储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
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别名
- CEACAM1,5
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背景
- Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
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UniProt
- P06731, P13688
抗原
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