GZMB 抗体
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- 抗原 See all GZMB 抗体
- GZMB (Granzyme B (GZMB))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GZMB antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Cell-ELISA (cELISA)
- 特异性
- GM4C1 recognises granzyme B transiently expressed on the cell surface of transfected BOSC cells as well as the native protein in peripheral blood mononuclear cells. The antibody does not cross-react with the human granzymes A, K or M (Fi
- 纯化方法
- Protein G
- 免疫原
- genetic immunisation with cDNA encoding human Granzyme B
- 克隆位点
- GM-4C1
- 亚型
- IgG1
- Top Product
- Discover our top product GZMB Primary Antibody
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- 应用备注
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - 限制
- 仅限研究用
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- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- 抗原
- GZMB (Granzyme B (GZMB))
- 别名
- Granzyme B (GZMB 产品)
- 背景
- Granzymes are exogenous serine proteases that are stored in the cytotoxic granules of activated T cells and NK cells. GM4C1 was generated by genetic immunisation and reacts with human granzyme B (GrB), a 27 kDa serine protease which cleaves target-cell proteins at specific aspartate residues.
- UniProt
- P10144
- 途径
- Apoptosis, Caspase Cascade in Apoptosis
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