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FMR1 抗体 (C-Term)

Cited in 7+ publications. This 小鼠 单克隆 anti-FMR1 antibody (Clone 6A15) specifically detects FMR1 in WB, ELISA, IF, IP 和 ICC. The antibody is reactive with Drosophila melanogaster samples.
产品编号 ABIN108598
发货至: 中国
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Quick Overview for FMR1 抗体 (C-Term) (ABIN108598)

抗原

See all FMR1 抗体
FMR1 (Fragile X Mental Retardation 1 (FMR1))

适用

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Drosophila melanogaster

宿主

  • 78
  • 19
  • 2
小鼠

克隆类型

  • 53
  • 46
单克隆

标记

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This FMR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

6A15
  • 抗原表位

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    C-Term

    无交叉反应

    交叉反应 (详细)

    Fruit fly (Drosophila melanogaster) Does not react with Human

    纯化方法

    Protein A

    免疫原

    His-dFMR1 fusion protein (Drosophilia melanogaster) (C-terminal 580aa).

    亚型

    IgG1
  • 应用备注

    Optimal antibody dilution should be determined by titration, however as a guideline try at IP: Use at 25 μg/mg of lysate WB: Use at an assay dependent dilution. Detects a band of approximately 85 kDa (predicted molecular weight: 82 kDa)

    说明

    Myeloma, fusion partners: SP2/0

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Callan, Clements, Ahrendt, Zarnescu: "Fragile X Protein is required for inhibition of insulin signaling and regulates glial-dependent neuroblast reactivation in the developing brain." in: Brain research, Vol. 1462, pp. 151-61, (2012) (PubMed).

    Lim, Lee, Choi, Kilman, Kim, Park, Jang, Allada, Choe: "The novel gene twenty-four defines a critical translational step in the Drosophila clock." in: Nature, Vol. 470, Issue 7334, pp. 399-403, (2011) (PubMed).

    Monzo, Dowd, Minden, Sisson: "Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila." in: Developmental biology, Vol. 340, Issue 2, pp. 408-18, (2010) (PubMed).

    Callan, Cabernard, Heck, Luois, Doe, Zarnescu: "Fragile X protein controls neural stem cell proliferation in the Drosophila brain." in: Human molecular genetics, Vol. 19, Issue 15, pp. 3068-79, (2010) (PubMed).

    Kwak, Drier, Barbee, Ramaswami, Yin, Wickens: "GLD2 poly(A) polymerase is required for long-term memory." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 38, pp. 14644-9, (2008) (PubMed).

    Monzo, Papoulas, Cantin, Wang, Yates, Sisson: "Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 48, pp. 18160-5, (2006) (PubMed).

    Wan, Dockendorff, Jongens, Dreyfuss: "Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein." in: Molecular and cellular biology, Vol. 20, Issue 22, pp. 8536-47, (2000) (PubMed).

  • 抗原

    FMR1 (Fragile X Mental Retardation 1 (FMR1))

    别名

    Drosophila FMR1

    背景

    Synonyms:
    Drosophila FMR1 antibody,dFMR antibody,dFMR1 antibody,dFXR antibody,Drosophila fragile X mentalretardation protein antibody,FMRP antibody,Fragile X mental retardation 1 antibody,Fragile X mental retardation1 protein antibody,fragile X mental retardation protein antibody,FRAXA antibody,Protein FMR1antibody

    基因ID

    37528, 23879

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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