LMAN1 抗体 (C-Term)
Quick Overview for LMAN1 抗体 (C-Term) (ABIN1077459)
抗原
See all LMAN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- C-Term
-
特异性
- At least two isoforms of ERGIC53 are known to exist.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- Mouse monoclonal ERGIC53 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ERGIC53.
-
亚型
- IgG1
-
-
-
-
应用备注
- ERGIC53 antibody can be used for detection of ERGIC53 by Western blot at 1 - 2 μg/mL.
-
说明
-
(CT) Endoplasmic reticulum-golgi intermediate compartment protein 53
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
储存条件
- 4 °C
-
储存方法
- ERGIC53 Monoclonal antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
-
有效期
- 12 months
-
-
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
-
别名
- LMAN1
-
背景
-
ERGIC53, also known as lectin mannose-binding 1 (LMAN1) protein is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Synonyms: Lectin mannose-binding 1, LMAN1, endoplasmic reticulum-golgi intermediate compartment protein 53, ERGIC-53, F5F8D, FMFD1, MCFD1, MR60, gp58 -
分子量
- 56 kDa (calculated)
-
基因ID
- 3998
-
NCBI登录号
- NP_005561
抗原
-