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LMAN1 抗体 (C-Term)

This anti-LMAN1 antibody is a 兔 单克隆 antibody detecting LMAN1 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN1077459
发货至: 中国

Quick Overview for LMAN1 抗体 (C-Term) (ABIN1077459)

抗原

See all LMAN1 抗体
LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

适用

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  • 1
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人, 小鼠

宿主

  • 39
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克隆类型

  • 35
  • 6
单克隆

标记

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This LMAN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1H6D8G7
  • 抗原表位

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    • 1
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    C-Term

    特异性

    At least two isoforms of ERGIC53 are known to exist.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Mouse monoclonal ERGIC53 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ERGIC53.

    亚型

    IgG1
  • 应用备注

    ERGIC53 antibody can be used for detection of ERGIC53 by Western blot at 1 - 2 μg/mL.

    说明

    (CT) Endoplasmic reticulum-golgi intermediate compartment protein 53

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    4 °C

    储存方法

    ERGIC53 Monoclonal antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

    有效期

    12 months
  • 抗原

    LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

    别名

    LMAN1

    背景

    ERGIC53, also known as lectin mannose-binding 1 (LMAN1) protein is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
    Synonyms: Lectin mannose-binding 1, LMAN1, endoplasmic reticulum-golgi intermediate compartment protein 53, ERGIC-53, F5F8D, FMFD1, MCFD1, MR60, gp58

    分子量

    56 kDa (calculated)

    基因ID

    3998

    NCBI登录号

    NP_005561
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