FOXP3 抗体 (C-Term)
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- 抗原 See all FOXP3 抗体
- FOXP3 (Forkhead Box P3 (FOXP3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This FOXP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.
- 亚型
- IgG
- Top Product
- Discover our top product FOXP3 Primary Antibody
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- 应用备注
- FOXP3 antibody can be used for detection of FOXP3 by Western blot at 1 - 2 μg/mL.
- 说明
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(CT) Forkhead box P3
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- FOXP3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- FOXP3 (Forkhead Box P3 (FOXP3))
- 别名
- FOXP3 (FOXP3 产品)
- 别名
- foxp3 antibody, FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, PIDX antibody, XPID antibody, JM2 antibody, scurfin antibody, sf antibody, RGD1562112 antibody, forkhead box P3 antibody, forkhead box P3a antibody, forkhead box P3 L homeolog antibody, FOXP3 antibody, foxp3a antibody, foxp3 antibody, foxp3.L antibody, Foxp3 antibody
- 背景
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FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Synonyms: Forkhead box P3, JM2, AIID, IPEX, PIDX, XPID, DIETER, scurfin - 分子量
- 47 kDa (calculated)
- 基因ID
- 50943
- NCBI登录号
- NP_054728
- 途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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