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FLT3 抗体 (N-Term)

This anti-FLT3 antibody is a 兔多克隆 antibody detecting FLT3 in WB, ELISA 和 IF. Suitable for 人和小鼠.

Western Blotting (WB) image for anti-Fms-Related tyrosine Kinase 3 (FLT3) (N-Term) antibody (ABIN1077372) (FLT3 抗体 (N-Term))

1 image

产品编号 ABIN1077372

发货至: 中国

Quick Overview for FLT3 抗体 (N-Term) (ABIN1077372)

抗原

See all FLT3 抗体

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

144
43
6
5
1
1
1
1
1
1

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

77
12
9
7
6
4
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1

This FLT3 antibody is un-conjugated

应用范围

114
68
42
42
38
34
19
12
11
10
8
7
3
2
1
1
1
1
1

Western Blotting (WB), ELISA, Immunofluorescence (IF)

Discover our top product FLT3 Primary Antibody

抗原表位
19

18

17

12

9

8

6

6

5

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

特异性

At least three isoforms of FLT3 are known to exist, this antibody will detect all isoforms.

纯化方法

Affinity chromatography purified via peptide column

免疫原

FLT3 antibody was raised against an 18 amino acid synthetic peptide near the center of human FLT3.

亚型

IgG
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody
FLT3 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibody
FLT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibody
FLT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody
FLT3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 FITC

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 PE

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibody
FLT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

FLT3 antibody can be used for detection of FLT3 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

说明

(NT) Fms-like tyrosine kinase 3

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

PBS containing 0.02 % Sodium azide.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

储存条件

4 °C

储存方法

FLT3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

有效期

12 months
抗原

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

别名

FLT3

背景

FLT3 is a member of the class III receptor tyrosine kinase family and its internal tandem duplication (ITD) is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. It is a membrane bound glycosylated protein that is expressed primarily in early hematopoietic progenitor cells. Upon binding its ligand FL, FLT3 activates multiple signaling pathways including the PI3K/Akt and Ras/MEK/MAPK pathways. In cells expressing FLT3-ITD, these pathways are constitutively on, resulting in abnormal cell growth and anti-apoptotic activity.
Synonyms: Fms-like tyrosine kinase 3, receptor-type tyrosine-protein kinase FLT3, CD135, FL cytokine receptor, fetal liver kinase 2, stem cell tyrosine kinase 1

分子量

109 kDa

基因ID

2322

NCBI登录号

NP_004110

途径

RTK signaling

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