PLG 抗体
Quick Overview for PLG 抗体 (ABIN105702)
抗原
See all PLG 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-101-208-0100
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Supplier
- Rockland
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原理
- Plasminogen Antibody
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交叉反应 （详细）
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Plasminogen [Human Plasma].
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产品特性
- Synonyms: goat anti-Plasminogen Antibody, Angiostatin antibody, Microplasmin antibody, Plasmin antibody, Plasmin heavy chain A antibody, Plasmin light chain B antibody, PLG antibody
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纯化方法
- Anti-Plasminogen is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.
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免疫原
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Immunogen: Plasminogen [Human Plasma]
Immunogen Type: Native Protein
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亚型
- IgG
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anti-Plasminogen (PLG) antibody
PLG 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen (PLG) (AA 191-433) antibodyPLG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen (PLG) (AA 1-810) antibodyPLG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen (PLG) (AA 21-120) antibodyPLG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10 unconjugated
anti-Plasminogen (PLG) (AA 274-560) antibodyPLG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen (PLG) antibodyPLG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen (PLG) (AA 1-810) antibodyPLG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Plasminogen (PLG) (AA 20-300) antibodyPLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen (PLG) (AA 582-812) antibodyPLG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen (PLG) (AA 636-665), (C-Term) antibodyPLG 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18479 unconjugated
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应用备注
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Application Note: Anti-Plasminogen Antibody has been tested by western blot. This product is suitable to be assayed against 1.0 μg of Plasminogen [Human Plasma] in a standard ELISA using Peroxidase conjugated Affinity Purified anti-Goat IgG [H&L] (Rabbit) code #605-4302 and (ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) code # ABTS-100 as a substrate for 30 minutes at room temperature. A working dilution of 1:4,000 to 1:16,000 of the reconstitution concentration is suggested for this product.
Western Blot Dilution: 1:2,000 - 1:10,000
ELISA Dilution: 1:20,000 - 1:100,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
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浓度
- 10.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- PLG (Plasminogen (PLG))
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别名
- PLG
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背景
- Background: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, it weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases, and several complement zymogens, such as C1 and C5. The cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also, it cleaves fibrin, thrombospondin, and von Willebrand factor. Its has roles in tissue remodeling and tumor invasion which may be modulated by CSPG4 and binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo. Plasmin is inactivated by alpha-2-antiplasmin immediately after dissociation from the clot.
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基因ID
- 5340
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UniProt
- P00747
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途径
- Complement System, Lipid Metabolism
抗原
-
