电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Seryl-tRNA Synthetase (SARS) (AA 2-233) 抗体 (FITC)

This anti- antibody is a 兔 多克隆 antibody detecting in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN1046073
发货至: 中国

Quick Overview for Seryl-tRNA Synthetase (SARS) (AA 2-233) 抗体 (FITC) (ABIN1046073)

抗原

See all Seryl-tRNA Synthetase (SARS) 抗体
Seryl-tRNA Synthetase (SARS)

适用

  • 28
  • 14
  • 14
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1

宿主

  • 26
  • 2

克隆类型

  • 27
  • 1
多克隆

标记

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
FITC

应用范围

  • 18
  • 9
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 2-233

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Serine--tRNA ligase, cytoplasmic protein (2-233AA)

    亚型

    IgG
  • 应用备注

    Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Seryl-tRNA Synthetase (SARS)

    别名

    SARS

    背景

    Background: Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:9431993, PubMed:26433229, PubMed:28236339). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (PubMed:9431993, PubMed:26433229, PubMed:28236339). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC (PubMed:24940000). Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at \\\'Lys-16\\\' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA (PubMed:19423848, PubMed:19423847, PubMed:24940000).

    Aliases: C78314 antibody, cytoplasmic antibody, EC 6.1.1.11 antibody, FLJ36399 antibody, sarS antibody, Sars1 antibody, Serine tRNA ligase 1, cytoplasmic antibody, Serine tRNA ligase antibody, Serine--tRNA ligase antibody, serine--tRNA ligase, cytoplasmic antibody, SerRS antibody, SERS antibody, Seryl tRNA Ser/Sec synthetase antibody, Seryl tRNA synthetase antibody, Seryl tRNA synthetase cytoplasmic antibody, Seryl-tRNA Ser/Sec synthetase antibody, Seryl-tRNA synthetase antibody, seryl-tRNA synthetase, cytoplasmic antibody, Seryl-tRNA(Ser/Sec) synthetase antibody, Strs antibody, SYSC_HUMAN antibody

    UniProt

    P49591
You are here:
Chat with us!