RRAGA 抗体 (AA 1-247) (FITC)
Quick Overview for RRAGA 抗体 (AA 1-247) (FITC) (ABIN1046029)
抗原
See all RRAGA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-247
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)
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亚型
- IgG
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应用备注
- Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RRAGA (Ras-Related GTP Binding A (RRAGA))
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别名
- RRAGA
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背景
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Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
Aliases: Adenovirus E3 14.7 kDa-interacting protein 1 antibody, FIP-1 antibody, Rag A antibody, RagA antibody, Ras-related GTP-binding protein A antibody, RRAGA antibody, RRAGA_HUMAN antibody
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UniProt
- Q7L523
抗原
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