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RRAGA 抗体 (AA 1-247) (FITC)

This anti-RRAGA antibody is a 兔 多克隆 antibody detecting RRAGA in ELISA 和 WB. Suitable for 人.
产品编号 ABIN1046029
发货至: 中国

Quick Overview for RRAGA 抗体 (AA 1-247) (FITC) (ABIN1046029)

抗原

See all RRAGA 抗体
RRAGA (Ras-Related GTP Binding A (RRAGA))

适用

  • 27
  • 11
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  • 1

宿主

  • 27

克隆类型

  • 26
  • 1
多克隆

标记

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  • 1
  • 1
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This RRAGA antibody is conjugated to FITC

应用范围

  • 14
  • 13
  • 11
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ELISA, Western Blotting (WB)
  • 抗原表位

    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-247

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)

    亚型

    IgG
  • 应用备注

    Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RRAGA (Ras-Related GTP Binding A (RRAGA))

    别名

    RRAGA

    背景

    Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

    Aliases: Adenovirus E3 14.7 kDa-interacting protein 1 antibody, FIP-1 antibody, Rag A antibody, RagA antibody, Ras-related GTP-binding protein A antibody, RRAGA antibody, RRAGA_HUMAN antibody

    UniProt

    Q7L523
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