Interleukin 17a 抗体
(1 reference)
Quick Overview for Interleukin 17a 抗体 (ABIN1043781)
抗原
See all Interleukin 17a (IL17A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 209-301-b32
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Supplier
- Rockland
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原理
- IL-17A Antibody
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交叉反应 （详细）
- This antibody is specific for human IL-17A protein.
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产品特性
- Synonyms: mouse anti-Interleukin-17A antibody, mouse anti-IL-17A antibody, IL-17A, Interleukin-17A, Cytotoxic T-Lymphocyte-associated Antigen 8, CTLA8, Interleukin-17, IL17, IL-17, Interleukin17
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纯化方法
- Anti-Human IL-17A (MOUSE) Monoclonal Antibody was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-IL-17A (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17A produced in E.coli followed by hybridoma development.
Immunogen Type: Recombinant Protein
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亚型
- IgG2b
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anti-Interleukin 17A (IL17A) (AA 1-75) antibody
IL17A 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4K5F6 unconjugated
anti-Interleukin 17A (IL17A) (Internal Region) antibodyIL17A 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 人 ELISA, WB, Neut 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) (AA 24-133) antibodyIL17A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 人 ELISA, FACS, ICC, IP 宿主: 小鼠 Monoclonal 9F9 unconjugated
anti-Interleukin 17A (IL17A) antibody (FITC)IL17A 适用: 人 ICFC 宿主: 小鼠 Monoclonal 9F9 FITC
anti-Interleukin 17A (IL17A) antibody (APC)IL17A 适用: 人 ICFC 宿主: 小鼠 Monoclonal 9F9 APC
anti-Interleukin 17A (IL17A) antibody (PE)IL17A 适用: 人 FACS 宿主: 小鼠 Monoclonal 9F9 PE
anti-Interleukin 17A (IL17A) (AA 24-155) antibodyIL17A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry Dilution: User Optimized
Application Note: Anti-Human IL-17A antibody has been tested for use in Western Blot and suitable in FLOW. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:10,000-1:50,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis." in: Journal of the American Society of Nephrology : JASN, Vol. 20, Issue 5, pp. 969-79, (2009) (PubMed).
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: "The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis." in: Journal of the American Society of Nephrology : JASN, Vol. 20, Issue 5, pp. 969-79, (2009) (PubMed).
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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别名
- IL17A
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背景
- Background: IL17-A (also known as Interleukin-17) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.
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基因ID
- 3605
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UniProt
- Q16552
抗原
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