PPP2CA 抗体 (meLys309)
(8 references)Quick Overview for PPP2CA 抗体 (meLys309) (ABIN1042659)
抗原
See all PPP2CA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- meLys309
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序列
- KLH-C-ßA-RRTPDYFL-OMe
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特异性
- Recognises specifically the C-terminally methylated form of PP2A C subunit
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交叉反应
- Saccharomyces cerevisiae
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交叉反应 （详细）
- Mouse, Rat, Human. Predicted to work with: Saccharomyces cerevisiae
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纯化方法
- Protein G
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免疫原
- A KLH-coupled peptide with the sequence: KLH-C-ßA-RRTPDYFL-OMe. The c-terminal sequence (as well as the carboxy-methylation) is absolutely conserved from human, mouse to yeast
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亚型
- IgG1
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anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (C-Term) antibody
PPP2CA 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 1-309) antibodyPPP2CA 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 1-309), (Catalytic Subunit alpha) antibodyPPP2CA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) antibodyPPP2CA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (Thr278) antibodyPPP2CA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 6-20), (N-Term) antibodyPPP2CA 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 1-309) antibodyPPP2CA 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (N-Term) antibodyPPP2CA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (C-Term) antibodyPPP2CA 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA) (AA 274-304), (C-Term) antibodyPPP2CA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB6000 unconjugated
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应用备注
- Optimal antibody dilution should be determined by titration, however as a guideline try, WB: 1,500. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa)
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说明
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Myeloma, fusion partners: X63-Ag8.653
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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: "Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells." in: The Journal of biological chemistry, Vol. 287, Issue 28, pp. 23451-63, (2012) (PubMed).
: "Microcystin-LR (MCLR) induces a compensation of PP2A activity mediated by ?4 protein in HEK293 cells." in: International journal of biological sciences, Vol. 7, Issue 6, pp. 740-52, (2011) (PubMed).
: "A stress survival response in retinal cells mediated through inhibition of the serine/threonine phosphatase PP2A." in: The European journal of neuroscience, Vol. 32, Issue 3, pp. 322-34, (2010) (PubMed).
: "Generation of active protein phosphatase 2A is coupled to holoenzyme assembly." in: PLoS biology, Vol. 5, Issue 6, pp. e155, (2007) (PubMed).
: "Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 11, pp. 2751-9, (2007) (PubMed).
: "Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 10, pp. 1080-91, (2004) (PubMed).
: "Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 4, pp. 287-301, (2004) (PubMed).
: "A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo." in: Genes & development, Vol. 17, Issue 17, pp. 2138-50, (2003) (PubMed).
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: "Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells." in: The Journal of biological chemistry, Vol. 287, Issue 28, pp. 23451-63, (2012) (PubMed).
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- PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
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别名
- PP2A alpha
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背景
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Synonyms:
PP2A alpha antibody,PP2A C antibody,PP2A-alpha antibody,PP2AA_HUMAN antibody,PP2Ac antibody,PP2CA antibody,PPP2CA antibody,Protein phosphatase 2, catalytic subunit, alpha isoform antibody,Replication protein C antibody -
基因ID
- 5515, 19052, 24672
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OMIM
- 176915
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UniProt
- P67775, P63330, P63331
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途径
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
抗原
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