SARS-CoV Spike 抗体 (Intermediate Domain 3)
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Quick Overview for SARS-CoV Spike 抗体 (Intermediate Domain 3) (ABIN1031207)
抗原
See all SARS-CoV Spike (SARS-CoV S) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Intermediate Domain 3
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预测反应
- Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 40%, homology 56%)
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
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Anti-SARS-CoV Spike antibody (3225) was raised against a peptide corresponding to 15 amino acids near the center of SARS-CoV Spike glycoprotein.
The immunogen is located within amino acids 650-700 of SARS-CoV Spike. -
亚型
- IgG
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anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 1124-1140) antibody
SARS-CoV S 适用: SARS Coronavirus (SARS-CoV) WB 宿主: 兔 Polyclonal unconjugated
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) antibodySARS-CoV S 适用: SARS Coronavirus (SARS-CoV) ELISA, WB, IF, IC 宿主: 小鼠 Monoclonal 3A2 unconjugated
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 401-500) antibody (AbBy Fluor® 488)SARS-CoV S 适用: SARS Coronavirus (SARS-CoV), Virus WB 宿主: 兔 Polyclonal AbBy Fluor® 488
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 19-35) antibodySARS-CoV S 适用: SARS Coronavirus (SARS-CoV) WB 宿主: 小鼠 Monoclonal unconjugated
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 755-769) antibodySARS-CoV S 适用: SARS Coronavirus (SARS-CoV) WB 宿主: 兔 Polyclonal unconjugated
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 288-303) antibodySARS-CoV S 适用: SARS Coronavirus (SARS-CoV) ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 19-35) antibodySARS-CoV S 适用: SARS Coronavirus (SARS-CoV) ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 13-42) antibodySARS-CoV S 适用: SARS Coronavirus (SARS-CoV) WB 宿主: 兔 Polyclonal RB3977-3978 unconjugated
anti-SARS-Coronavirus Spike Protein (SARS-CoV S) (AA 532-562) antibodySARS-CoV S 适用: SARS Coronavirus (SARS-CoV) WB 宿主: 兔 Polyclonal RB3983-3984 unconjugated
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应用备注
- SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 5 ng of free peptide at 1 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- The antibody is supplied in PBS containing 0.02% sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- 4 °C/-20 °C
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储存方法
- The antibody can be stored at 4 ˚ C for three months and -20 ˚ C, stable for up to one year.
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有效期
- 12 months
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- SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))
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别名
- SARS-CoV Spike
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物质类
- Viral Protein
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背景
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection. The spike protein is the major target for neutralizing antibodies and vaccine development. The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19. The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein .
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基因ID
- 1489668
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NCBI登录号
- P59594
抗原
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