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ACR-Modified Keyhole-Lympet Hemocyanine 抗体

This anti- antibody is a 小鼠 单克隆 antibody detecting in IHC. Suitable for . This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1020376
发货至: 中国

Quick Overview for ACR-Modified Keyhole-Lympet Hemocyanine 抗体 (ABIN1020376)

抗原

ACR-Modified Keyhole-Lympet Hemocyanine

宿主

小鼠

克隆类型

单克隆

应用范围

Immunohistochemistry (IHC)

克隆位点

5F6
  • 特异性

    Specific for ACR-modified protein (especially FDP-lysine type derivative).

    纯化方法

    Protein A purified

    亚型

    IgG1 kappa
  • 应用备注

    Recommended antibody concentration is 0.5-1.0 µg/mL on paraformaldehyde fixed tissue.

    限制

    仅限研究用
  • 状态

    Frozen

    缓冲液

    100 µg/mL antibody in 10mM PBS containing 0.1% NaN3 and 0.5% BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Sugiyama, Sun, Nishinohara, Fujita, Masuda, Ochi, Takeuchi: "Expressions of lipid oxidation markers, N(ε)-hexanoyl lysine and acrolein in cisplatin-induced nephrotoxicity in rats." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 73, Issue 6, pp. 821-6, (2011) (PubMed).

  • 抗原

    ACR-Modified Keyhole-Lympet Hemocyanine

    背景

    Acrolein (ACR) is a representative carcinogenic aldehyde found ubiquitously in the environment and formed endogenously through oxidation reactions, such as lipid peroxidation and myeloperoxidasecatalyzed amino acid oxidation. ACR is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with ACR and lysine residue leads to the formation of numerous numbers of adducts, such as formyl-dehydropiperidino-lysine (FDP-lysine) type derivative. This antibody is specific for the ACR-modified protein, especially FDP-lysine type derivative.
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