Angiotensin II/III 抗体
(Angiotensin II/III (Ang II/III))
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008].
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Angiotensin II/III 抗体
High quality antibodies with extensive validation data.
Recommended Angiotensin II/III 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN211453
Quantity
0.2 mg
Datasheet
Datasheet
Reactivity
Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
Application
ELISA
Validations
Cat. No.
ABIN1822131
Quantity
400 μg
Datasheet
Datasheet
Latest Publications for our Angiotensin II/III Products
: "Renin-angiotensin system activation and imbalance of matrix metalloproteinase-9/tissue inhibitor of matrix metalloproteinase-1 in cold-induced stroke." in: Life sciences, Vol. 231, pp. 116563, (2019) (PubMed).: "Tumor necrosis factor α-converting enzyme inhibitor attenuates lipopolysaccharide-induced reactive oxygen species and mitogen-activated protein kinase expression in human renal proximal tubule ..." in: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, Vol. 22, Issue 2, pp. 135-143, (2018) (PubMed).
: "A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction." in: Scientific reports, Vol. 7, pp. 43920, (2017) (PubMed).
: "Age-related changes in bladder function with altered angiotensin II receptor mechanisms in rats." in: Neurourology and urodynamics, Vol. 35, Issue 8, pp. 908-913, (2015) (PubMed).
: "Angiotensin-(1-7) Attenuates Kidney Injury Due to Obstructive Nephropathy in Rats." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142664, (2015) (PubMed).
: "Renal denervation attenuates progression of atherosclerosis in apolipoprotein E-deficient mice independent of blood pressure lowering." in: Hypertension, Vol. 65, Issue 4, pp. 758-65, (2015) (PubMed).
: "Activation of renin-angiotensin system is involved in dyslipidemia-mediated renal injuries in apolipoprotein E knockout mice and HK-2 cells." in: Lipids in health and disease, Vol. 12, pp. 49, (2014) (PubMed).
: "Critical role of matrix metalloproteinase-9 in acute cold exposure-induced stroke in renovascular hypertensive rats." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 22, Issue 8, pp. e477-85, (2013) (PubMed).
: "Interaction of RAS activation and lipid disorders accelerates the progression of glomerulosclerosis." in: International journal of medical sciences, Vol. 10, Issue 12, pp. 1615-24, (2013) (PubMed).
Synonyms and alternative names related to Angiotensin II/III
angiotensinogen (AGT), ANHU, SERPINA8Protein level used designations for Angiotensin II/III
- alpha-1 antiproteinase, antitrypsin
- angiotensin I
- angiotensin II
- angiotensinogen
- pre-angiotensinogen
- serine (or cysteine) proteinase inhibitor
- serpin A8
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