ANAPC5 蛋白
(Anaphase Promoting Complex Subunit 5 (ANAPC5))
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ANAPC5 Protein (AA 1-740) (His tag) | 小鼠 | HEK-293 Cells |
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| ANAPC5 Protein (AA 1-755) (His tag) | 人 | HEK-293 Cells |
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| ANAPC5 Protein (AA 1-755) (GST tag) | 人 | 小麦胚 |
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| ANAPC5 Protein (AA 1-755) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| ANAPC5 Protein (AA 1-740) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| ANAPC5 Protein (AA 2-232, partial) (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| ANAPC5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| ANAPC5 Protein (AA 1-727) (His tag) | 大鼠 | 酵母菌 |
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Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 所列应用)
5 references - 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- 90 %
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Latest Publications for our ANAPC5 蛋白
: "The full-ORF clone resource of the German cDNA Consortium." in: BMC genomics, Vol. 8, pp. 399, (2008) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).
: "Mitotic regulation of the human anaphase-promoting complex by phosphorylation." in: The EMBO journal, Vol. 22, Issue 24, pp. 6598-609, (2003) (PubMed).
: "Identification of a cullin homology region in a subunit of the anaphase-promoting complex." in: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1219-22, (1998) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).
: "Mitotic regulation of the human anaphase-promoting complex by phosphorylation." in: The EMBO journal, Vol. 22, Issue 24, pp. 6598-609, (2003) (PubMed).
: "Identification of a cullin homology region in a subunit of the anaphase-promoting complex." in: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1219-22, (1998) (PubMed).
Aliases for ANAPC5 蛋白
anaphase promoting complex subunit 5 (ANAPC5) 蛋白anaphase promoting complex subunit 5 (anapc5) 蛋白
anaphase-promoting complex subunit 5 (LOC100093215) 蛋白
anaphase promoting complex subunit 5 L homeolog (anapc5.L) 蛋白
anaphase-promoting complex subunit 5 (Anapc5) 蛋白
anaphase-promoting complex subunit (AT1G06590) 蛋白
anaphase-promoting complex subunit Apc5 (apc5) 蛋白
anaphase promoting complex subunit 5 (Anapc5) 蛋白
2510006G12Rik 蛋白
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AA536819 蛋白
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DDBDRAFT_0206386 蛋白
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F12K11.7 蛋白
F12K11_7 蛋白
MGC89697 蛋白
wu:fb75a09 蛋白
zgc:55800 蛋白
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