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抗Human CAMKK1 抗体:
抗Mouse (Murine) CAMKK1 抗体:
抗Rat (Rattus) CAMKK1 抗体:
Human Polyclonal CAMKK1 Primary Antibody for ICC, IF - ABIN446068
Hamada, Souda, Yoshimura, Sasaguri, Hatanaka, Tasaki, Yoshioka, Ohi, Yamada, Tsutsui, Umekita, Tanimoto: Anti-apoptotic effects of PCP4/PEP19 in human breast cancer cell lines: a novel oncotarget. in Oncotarget 2014
Site-directed mutagenesis analysis revealed that Leu(358) in CaMKKbeta/Ile(322) in CaMKKalpha confer, at least in part, a distinct recognition of AMPK but not of CaMKIalpha.
CaMKK1 does not play a pivotal role in the calcium signaling cascade regulating adrenal aldosterone production.
CAMKK1 might contribute to the risk of lung cancer in Chinese populations.
role for CaMKKalpha in the differentiation of monocytic cells
CaMKIalpha is a widely expressed protein kinase, suggesting that Ca2+ is likely to be functionally important in the control of mitochondrial dynamics through regulation of Drp1 phosphorylation in neurons and other cell types.[CaMKIalpha]
Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways
the CaMKK-CaMKIalpha cascade is required for the axonal growth effect of Wnt5a during neuronal polarization.
Data (including data from knockout mice) suggest that up-regulation of Camkk1 and calcium signaling stimulates muscle growth via up-regulation of mTORC1 (mammalian target of rapamycin complex 1) signaling and muscle protein biosynthesis.
caCaMKKalpha stimulates glucose uptake additively with insulin, and in insulin-resistant muscle, and alters the phosphorylation of TBC1D1/TBC1D4.
ERK activation and neurite outgrowth in response to depolarization are mediated by CaMKK activation of CaMKI
In muscles from wild-type mice CaMKKalpha increased in vivo deoxyglucose uptake and AMPKalpha1 and -alpha2 activities 2.5-fold.
Data show that CaMKK is the kinase responsible for alpha-lipoic acid induced AMP-activated protein kinase activation in C2C12 myotubes.
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.
, camkk 1
, calcium/calmodulin-dependent protein kinase kinase 1
, calcium/calmodulin-dependent protein kinase kinase 1, alpha
, calcium/calmodulin-dependent protein kinase 1 alpha-like
, calcium/calmodulin-dependent protein kinase kinase 1-like
, CAMKK alpha protein
, caM-KK 1
, caM-KK alpha
, caM-kinase IV kinase
, caM-kinase kinase 1
, caM-kinase kinase alpha
, caMKK 1
, calcium/calmodulin-dependent protein kinase kinase alpha
, caMKK alpha
, calcium calmodulin dependent protein kinase kinase alpha
, alpha CaMKK