Aminoacylase 1 抗体
(Aminoacylase 1 (ACY1))
This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Nov 2010].
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38 results :
ACY1
适用: 人, 小鼠, 大鼠, 犬
WB, IHC, FACS, IHC (p)
宿主: 小鼠
Monoclonal
2D3
unconjugated
ACY1
适用: 人, 犬, 猴
WB, IHC, FACS, IHC (p)
宿主: 小鼠
Monoclonal
2F1
unconjugated
ACY1
适用: 人
WB, IHC, IF
宿主: 兔
Polyclonal
unconjugated
ACY1
适用: 人
WB, IHC, ELISA
宿主: 兔
Polyclonal
unconjugated
ACY1
适用: 人
WB, ELISA
宿主: 小鼠
Polyclonal
unconjugated
1 image
2 references
ACY1
适用: 人
WB, IHC, ELISA, IF, IP, IHC (p)
宿主: 小鼠
Monoclonal
4F1-B7
unconjugated
ACY1
适用: 大鼠
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our Aminoacylase 1 抗体
: "Profiling of antibody production against xenograft-released proteins by protein microarrays discovers prostate cancer markers." in: Journal of proteome research, Vol. 11, Issue 2, pp. 728-35, (2012) (PubMed).: "The molecular basis of aminoacylase 1 deficiency." in: Biochimica et biophysica acta, Vol. 1812, Issue 6, pp. 685-90, (2011) (PubMed).
: "Acylase 1 expression in rat intestinal crypt--villus axis." in: Cell biology international, Vol. 31, Issue 9, pp. 966-73, (2007) (PubMed).
: "Aminoacylase I deficiency: a novel inborn error of metabolism." in: Biochemical and biophysical research communications, Vol. 338, Issue 3, pp. 1322-6, (2005) (PubMed).
Aliases for Aminoacylase 1 抗体
aminoacylase 1 (ACY1) 抗体aminoacylase 1 (acy1) 抗体
aminoacylase 1, gene 1 S homeolog (acy1.1.S) 抗体
aminoacylase 1, gene 1 (acy1.1) 抗体
aminoacylase 1 (Acy1) 抗体
1110014J22Rik 抗体
ACY-1 抗体
Acy-1 抗体
acy1 抗体
ACY1 抗体
Acy1a 抗体
Acy1b 抗体
acy1d 抗体
ACY1D 抗体
acylase 抗体
si:zfos-226g1.1 抗体
zgc:55605 抗体
zgc:76955 抗体
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