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alpha Adducin 产品

(Adducin 1 (Alpha) (ADD1))

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Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms\; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].

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Featured alpha Adducin Categories

alpha Adducin 抗体

High quality antibodies with extensive validation data.

alpha Adducin 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our alpha Adducin Products

Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).

Lin, Nasir, McDonald, Graham, Rommens, Goldberg, Hayden: "Genomic organization of the human alpha-adducin gene and its alternately spliced isoforms." in: Genomics, Vol. 25, Issue 1, pp. 93-9, (1995) (PubMed).

Taylor, Snell, Buckler, Ambrose, Duyao, Church, Lin, Altherr, Bates, Groot: "Cloning of the alpha-adducin gene from the Huntington's disease candidate region of chromosome 4 by exon amplification." in: Nature genetics, Vol. 2, Issue 3, pp. 223-7, (1994) (PubMed).

Joshi, Gilligan, Otto, McLaughlin, Bennett: "Primary structure and domain organization of human alpha and beta adducin." in: The Journal of cell biology, Vol. 115, Issue 3, pp. 665-75, (1991) (PubMed).

Synonyms and alternative names related to alpha Adducin

adducin 1 (ADD1), adducin 1 (alpha) (Add1), adducin 1 (Add1), adducin 1 (alpha) (add1), adducin 1 (add1), adducin 1 S homeolog (add1.S), ADD1, add1-a, add2, ADDA, adda, AI256389, alpha-adducin, bZ1H20.1, cb787, zgc:158352

Protein level used designations for alpha Adducin

  • alpha-adducin
  • erythrocyte adducin alpha subunit
  • erythrocyte adducin subunit alpha
  • alpha-ADD
  • adducin 1 (alpha)
  • alpha-adducin-like
  • adducin 2 (beta)
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