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ALOX5AP 抗体

(Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].

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  • 抗原: ALOX5AP
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7969882
ALOX5AP 抗体 (Middle Region) (Fluoro647) ALOX5AP · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • 100 μg
发货至: 中国
ABIN7969881
ALOX5AP 抗体 (Middle Region) (PE) ALOX5AP · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • 100 μg
发货至: 中国
ABIN7834197
ALOX5AP 抗体 ALOX5AP · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • 200 μL
发货至: 中国
ABIN7879996
ALOX5AP 抗体 ALOX5AP · Primary Antibody 人 山羊 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN7879504
ALOX5AP 抗体 (Middle Region) ALOX5AP · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • 100 μg
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Fluoro647
抗体亚型
IgG
抗原表位
Middle Region
产品编号 ABIN7969882
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
PE
抗体亚型
IgG
抗原表位
Middle Region
产品编号 ABIN7969881
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
产品编号 ABIN7834197
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • ELISA (ELISA: 所列应用)
适用
人
宿主
山羊
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
Ig Fraction
产品编号 ABIN7879996
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
Middle Region
产品编号 ABIN7879504

Latest Publications for our ALOX5AP 抗体

Schmider, Vaught, Bauer, Elliott, Godin, Ellis, Nigrovic, Soberman: "The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses." in: PLoS ONE, Vol. 14, Issue 2, pp. e0211943, (2019) (PubMed).

Huang, Sharifpanah, Becker, Wartenberg, Sauer: "Impact of Arachidonic Acid and the Leukotriene Signaling Pathway on Vasculogenesis of Mouse Embryonic Stem Cells." in: Cells, tissues, organs, Vol. 201, Issue 5, pp. 319-32, (2016) (PubMed).

Elias, Ferré, Vilà, Muñoz, Casellas, Garcia, Molas, Agudo, Roca, Ruberte, Bosch, Franckhauser: "ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance." in: Diabetes, Vol. 65, Issue 8, pp. 2139-50, (2016) (PubMed).

Perisic, Hedin, Razuvaev, Lengquist, Osterholm, Folkersen, Gillgren, Paulsson-Berne, Ponten, Odeberg, Hedin: "Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, Issue 10, pp. 2432-43, (2013) (PubMed).

Finkensieper, Kieser, Bekhite, Richter, Mueller, Graebner, Figulla, Sauer, Wartenberg: "The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells." in: Cardiovascular research, Vol. 86, Issue 1, pp. 37-44, (2010) (PubMed).

Maier, Tausch, Hoernig, Coste, Schmidt, Angioni, Metzner, Groesch, Pergola, Steinhilber, Werz, Geisslinger: "Celecoxib inhibits 5-lipoxygenase." in: Biochemical pharmacology, Vol. 76, Issue 7, pp. 862-72, (2008) (PubMed).

Kaaman, Rydén, Axelsson, Nordström, Sicard, Bouloumié, Langin, Arner, Dahlman: "ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance." in: International journal of obesity (2005), Vol. 30, Issue 3, pp. 447-52, (2006) (PubMed).

Helgadottir, Manolescu, Thorleifsson, Gretarsdottir, Jonsdottir, Thorsteinsdottir, Samani, Gudmundsson, Grant, Thorgeirsson, Sveinbjornsdottir, Valdimarsson, Matthiasson, Johannsson, Gudmundsdottir et al.: "The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. ..." in: Nature genetics, Vol. 36, Issue 3, pp. 233-9, (2004) (PubMed).

Liu, Yin: "Identification of the binding partners for flightless I, A novel protein bridging the leucine-rich repeat and the gelsolin superfamilies." in: The Journal of biological chemistry, Vol. 273, Issue 14, pp. 7920-7, (1998) (PubMed).

Aliases for ALOX5AP 抗体

arachidonate 5-lipoxygenase-activating protein (alox5ap) 抗体
arachidonate 5-lipoxygenase activating protein (ALOX5AP) 抗体
arachidonate 5-lipoxygenase activating protein (alox5ap) 抗体
arachidonate 5-lipoxygenase activating protein (Alox5ap) 抗体
al5ap 抗体
Alox5ap 抗体
ALOX5AP 抗体
fj65d02 抗体
flap 抗体
Flap 抗体
FLAP 抗体
wu:fj65d02 抗体
zgc:63982 抗体
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