AKR1C3 抗体
(Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| AKR1C3 抗体 (Alexa Fluor 750) | 人 | 兔 Polyclonal |
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| AKR1C3 抗体 (Alexa Fluor 594) | 人 | 兔 Polyclonal |
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| AKR1C3 抗体 (Alexa Fluor 488) | 人 | 兔 Polyclonal |
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| AKR1C3 抗体 (Biotin) | 人 | 兔 Polyclonal |
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| Recombinant AKR1C3 抗体 | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 21A20
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Latest Publications for our AKR1C3 抗体
: "Production of prostaglandins in placentae and corpus luteum in pregnant hinds of red deer (Cervus elaphus)." in: Theriogenology, Vol. 85, Issue 4, pp. 762-8, (2016) (PubMed).
: "Interindividual variability in the cardiac expression of anthracycline reductases in donors with and without Down syndrome." in: Pharmaceutical research, Vol. 31, Issue 7, pp. 1644-55, (2014) (PubMed).
: "Induction of PGF2? synthesis by cortisol through GR dependent induction of CBR1 in human amnion fibroblasts." in: Endocrinology, Vol. 155, Issue 8, pp. 3017-24, (2014) (PubMed).
: "Testosterone synthesis in patients with 17β-hydroxysteroid dehydrogenase 3 deficiency." in: Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation, Vol. 6, Issue 4, pp. 161-8, (2012) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate." in: Urology, Vol. 65, Issue 1, pp. 76-82, (2005) (PubMed).
: "Interindividual variability in the cardiac expression of anthracycline reductases in donors with and without Down syndrome." in: Pharmaceutical research, Vol. 31, Issue 7, pp. 1644-55, (2014) (PubMed).
: "Induction of PGF2? synthesis by cortisol through GR dependent induction of CBR1 in human amnion fibroblasts." in: Endocrinology, Vol. 155, Issue 8, pp. 3017-24, (2014) (PubMed).
: "Testosterone synthesis in patients with 17β-hydroxysteroid dehydrogenase 3 deficiency." in: Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation, Vol. 6, Issue 4, pp. 161-8, (2012) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate." in: Urology, Vol. 65, Issue 1, pp. 76-82, (2005) (PubMed).
Aliases for AKR1C3 抗体
aldo-keto reductase family 1, member C3 L homeolog (akr1c3.L) 抗体aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR1C3) 抗体
aldo-keto reductase family 1 member C2 (LOC722496) 抗体
aldo-keto reductase family 1 member C3 (AKR1C3) 抗体
aldo-keto reductase family 1, member C3 (Akr1c3) 抗体
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