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AKR1C2 抗体

(Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

Active filters:

  • 抗原: AKR1C2
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6826853
AKR1C2 抗体 (Alexa Fluor 594) AKR1C2 · Primary Antibody 人 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6810790
AKR1C2 抗体 (Alexa Fluor 488) AKR1C2 · Primary Antibody 人 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN7649362
AKR1C2 抗体 AKR1C2 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 CPTC-AKR1C2-1
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
  • 100 μL
  • 500 μL
发货至: 中国
ABIN7649363
AKR1C2 抗体 AKR1C2 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 CPTC-AKR1C2-1
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
  • 50 μL
发货至: 中国
ABIN2907118
AKR1C2 抗体 (AA 1-323) AKR1C2 · Primary Antibody 人, 大鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 100 μL
  • 20 μL
  • 50 μL
发货至: 中国
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 594
产品编号 ABIN6826853
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 488
产品编号 ABIN6810790
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
CPTC-AKR1C2-1
标记
unconjugated
抗体亚型
IgG2a, kappa
产品编号 ABIN7649362
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
CPTC-AKR1C2-1
标记
unconjugated
抗体亚型
IgG2a, kappa
产品编号 ABIN7649363
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
适用
人, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 1-323
产品编号 ABIN2907118
100 μL (More quantities available)
发货至: 中国
获取报价

Latest Publications for our AKR1C2 抗体

Ebert, Kisiela, Wsól, Maser: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).

Hevir, Vouk, Sinkovec, Ribi?-Pucelj, Rižner: "Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 217-26, (2011) (PubMed).

Takahashi, Bains, Pfeifer, Grigliatti, Reid, Riggs: "Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 6, pp. 991-4, (2008) (PubMed).

Su, Liao, Huang, Chu, Lin, Chang: "Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis." in: Toxicology, Vol. 244, Issue 2-3, pp. 257-70, (2008) (PubMed).

Aliases for AKR1C2 抗体

aldo-keto reductase family 1 member C2 (AKR1C2) 抗体
aldo-keto reductase family 1, member C2 (Akr1c2) 抗体
AKR1C-pseudo 抗体
Akr1c21 抗体
BABP 抗体
DD 抗体
DD2 抗体
DDH2 抗体
HAKRD 抗体
HBAB 抗体
MCDR2 抗体
SRXY8 抗体
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