(ADAM Metallopeptidase with thrombospondin Type 1 Motif, 9 (ADAMTS9))
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. [provided by RefSeq, Jul 2008].
Choi, Halbritter, Braun, Schueler, Schapiro, Rim, Nandadasa, Choi, Widmeier, Shril, Körber, Sethi, Lifton, Beck, Apte, Gee, Hildebrandt: "Mutations of ADAMTS9 Cause Nephronophthisis-Related Ciliopathy." in: American journal of human genetics, Vol. 104, Issue 1, pp. 45-54, (2019) (PubMed).
Peluffo, Murphy, Baughman, Stouffer, Hennebold: "Systematic analysis of protease gene expression in the rhesus macaque ovulatory follicle: metalloproteinase involvement in follicle rupture." in: Endocrinology, Vol. 152, Issue 10, pp. 3963-74, (2011) (PubMed).
Aliases for ADAMTS9 抗体
ADAM metallopeptidase with thrombospondin type 1 motif 9 (ADAMTS9) 抗体 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 (Adamts9) 抗体 ADAM metallopeptidase with thrombospondin type 1 motif, 9 (Adamts9) 抗体 1810011L16Rik 抗体 8430403M15Rik 抗体 AW743315 抗体 E030027K14Rik 抗体