ADAM22 抗体
(ADAM Metallopeptidase Domain 22 (ADAM22))
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010].
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Latest Publications for our ADAM22 抗体
: "Comparative synaptosome imaging: a semi-quantitative method to obtain copy numbers for synaptic and neuronal proteins." in: Scientific reports, Vol. 8, Issue 1, pp. 14838, (2018) (PubMed).: "Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes." in: Biochimica et biophysica acta, Vol. 1854, Issue 7, pp. 827-33, (2015) (PubMed).
: "The Polarity Protein Pals1 Regulates Radial Sorting of Axons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 29, pp. 10474-84, (2015) (PubMed).
: "Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis." in: Annals of neurology, Vol. 71, Issue 5, pp. 601-13, (2012) (PubMed).
: "ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 3, pp. 1038-48, (2010) (PubMed).
: "LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 19, pp. 6607-12, (2010) (PubMed).
: "Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy." in: Nature medicine, Vol. 15, Issue 10, pp. 1208-14, (2009) (PubMed).
Aliases for ADAM22 抗体
a disintegrin and metallopeptidase domain 22 (Adam22) 抗体ADAM metallopeptidase domain 22 (Adam22) 抗体
ADAM metallopeptidase domain 22 (ADAM22) 抗体
ADAM metallopeptidase domain 22 L homeolog (adam22.L) 抗体
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ADAM 22 抗体
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