(Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Muroya, Ito, Rong, Takashima, Ito, Cao, Nakamura, Joh, Kohzuki: "Disorder of fatty acid metabolism in the kidney of PAN-induced nephrotic rats." in: American journal of physiology. Renal physiology, Vol. 303, Issue 7, pp. F1070-9, (2012) (PubMed).
Aliases for ACADVL 蛋白
acyl-CoA dehydrogenase very long chain (ACADVL) 蛋白 acyl-Coenzyme A dehydrogenase, very long chain (Acadvl) 蛋白 acyl-CoA dehydrogenase, very long chain (Acadvl) 蛋白 acyl-CoA dehydrogenase very long chain (acadvl) 蛋白 acyl-CoA dehydrogenase very long chain (Acadvl) 蛋白 ACAD6 蛋白 fb52d04 蛋白 LCACD 蛋白 VLCAD 蛋白 vlcad 蛋白 wu:fb52d04 蛋白 wu:fc75e01 蛋白 zgc:64067 蛋白