anti-Vpx Protein 抗体
Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells.
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anti-Vpx Protein (VPX) (AA 1-113), (subtype A) 抗体 Primary Antibody
anti-Vpx Protein (VPX) (AA 1-113), (subtype A) 抗体 (HRP) Primary Antibody
anti-Vpx Protein (VPX) (AA 1-113), (subtype A) 抗体 (FITC) Primary Antibody
anti-Vpx Protein (VPX) (AA 1-113), (subtype A) 抗体 (Biotin) Primary Antibody
Vpx Protein (VPX) 抗原简介
蛋白简介
Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity). {ECO:0000250}.
Gene names and symbols associated with anti-Vpx Protein (VPX) 抗体
- vpx protein (vpx) 抗体
Protein level used designations for anti-Vpx Protein (VPX) 抗体
Viral protein X , X ORF protein
| GENE ID | SPECIES |
|---|---|
| 1490006 | Simian immunodeficiency virus |
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